Polynucleotides are long chains of nucleotides—the fundamental components of DNA and RNA. In aesthetic medicine, they are typically sourced from purified salmon DNA due to its exceptional compatibility with human tissue.
When administered into the skin, polynucleotides work in multiple ways:
Stimulating fibroblasts to boost collagen and elastin production
Supporting cellular repair and regeneration, aiding recovery from damage and stress
Delivering deep hydration by binding water molecules, improving elasticity and suppleness
Reducing inflammation and oxidative stress, offering protection at the cellular level
Unlike traditional dermal fillers that primarily restore volume, polynucleotides focus on improving the health, structure, and function of the skin itself. This regenerative approach gradually enhances tone, texture, and luminosity, making it an excellent choice for those seeking natural, long-lasting skin rejuvenation.
Polynucleotide injections are highly versatile and can be applied to many areas of the face, neck, and body where the skin shows signs of aging, damage, or stress. Because of their gentle yet restorative nature, they are especially suitable for delicate regions that may not tolerate traditional injectables.
Common treatment areas include:
Under-eyes: Helps improve dark circles, hollowness, puffiness, and fine lines for a fresher, brighter look.
Cheeks: Restores elasticity, smooths texture, and enhances natural radiance.
Neck & décolletage: Addresses crepey skin, lines, and sun damage for a more youthful appearance.
Hands & arms: Improves skin thickness, hydration, and resilience in areas often prone to early aging.
Scalp: Supports both scalp health and hair vitality, making it beneficial for those experiencing thinning or weak hair.
By targeting these areas, polynucleotides don’t just mask signs of aging—they actively repair, hydrate, and strengthen the skin from within, offering natural-looking and long-lasting improvements.
Polynucleotide treatments are especially effective in areas where the skin is thin, fragile, or showing early signs of aging such as fine lines, loss of elasticity, or crepiness. They are commonly used on the under-eye region, cheeks, neck, décolletage, and even the scalp to restore vitality and promote healthier skin function.
Key benefits include:
Smoothing fine lines and wrinkles for a more youthful appearance
Enhancing overall skin tone and texture
Reducing the visibility of acne scars and stretch marks
Brightening under-eye circles and reducing puffiness
Firming thin, crepey skin and improving resilience
Deeply restoring hydration and elasticity
Gentle enough for sensitive or rosacea-prone skin
Important to note: Polynucleotide treatments are derived from fish DNA, making them unsuitable for vegetarians, vegans, or individuals with fish allergies. They are also not recommended during pregnancy or breastfeeding.
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